Wegovy

Buy Wegovy Online

How does wegovy work?

Wegovy is the brand name for semaglutide, a prescription medication created by Novo Nordisk. It is specifically approved for managing chronic weight in adults and adolescents who are overweight or obese. Wegovy falls under a class of drugs known as glucagon-like peptide-1 (GLP-1) receptor agonists, which imitate the effects of the natural hormone GLP-1. This hormone is involved in controlling appetite, food intake, and blood sugar levels.

Wegovy functions by targeting GLP-1 receptors in the brain and throughout the body, resulting in:

Appetite Suppression: It delays gastric emptying and affects appetite centers in the brain, helping individuals feel full more quickly and decreasing overall calorie intake.
Weight Loss: The combination of reduced appetite and lower calorie consumption leads to significant weight loss over time.
Blood Sugar Regulation: While Wegovy is primarily indicated for weight loss, it also helps lower blood glucose levels, making it advantageous for those with prediabetes or insulin resistance.
Indications

Wegovy is approved for:

Chronic Weight Management: For adults and adolescents aged 12 years and older who meet certain criteria:
Adults with a Body Mass Index (BMI) of ≥30 (obesity) or ≥27 (overweight) with at least one weight-related health issue, such as type 2 diabetes, hypertension, or dyslipidemia.
Adolescents with obesity and a BMI in the 95th percentile or higher for their age and sex.

Administration

Wegovy is given as a subcutaneous injection once a week. It comes in pre-filled injection pens with dosage strengths of 0.25 mg, 0.5 mg, 1.0 mg, 1.7 mg, and 2.4 mg. The dosage is usually increased gradually over several weeks to help reduce side effects:

Start with 0.25 mg once a week for 4 weeks.

Increase the dose every 4 weeks until reaching the target dose of 2.4 mg.

Clinical Benefits

Wegovy has shown impressive results in clinical trials:

Significant Weight Loss: Participants lost an average of 15-20% of their body weight over 68 weeks when combined with diet and exercise.

Improvements in Metabolic Health: There were reductions in waist circumference, better cholesterol levels, and lower blood pressure.
Delayed Progression to Type 2 Diabetes: For those with prediabetes, Wegovy lowers the risk of developing type 2 diabetes.

Wegovy Side Effects

The most frequently reported side effects of Wegovy are related to the gastrointestinal system and are generally mild to moderate:

Nausea (the most common)
Vomiting
Diarrhea
Constipation
Abdominal pain

Other possible side effects include:

Fatigue
Dizziness
Reactions at the injection site
Changes in taste
Rare but serious side effects may involve:

Pancreatitis: Inflammation of the pancreas.

Gallbladder Issues: Such as gallstones or inflammation (cholecystitis).
Thyroid C-cell Tumors: Although rare, this potential risk was noted in animal studies, so caution is advised for individuals with a family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).

Wegovy Contraindications

Wegovy should not be used by:

Individuals with a personal or family history of medullary thyroid carcinoma or MEN 2.
Those who have a known hypersensitivity to semaglutide or any of its components.
Pregnant women, as weight loss medications are not recommended during pregnancy.

Monitoring and Precautions

Weight Loss Progress: It’s important to have regular check-ins to track weight and ensure that the treatment plan is being followed.
Gastrointestinal Tolerance: Watch for any severe nausea or signs of dehydration.
Blood Sugar Levels: This is particularly crucial for those with prediabetes or type 2 diabetes.
Kidney Function: Monitoring is essential for individuals at risk of dehydration due to ongoing vomiting or diarrhea.

Comparisons to Other Treatments

Wegovy is frequently compared to other GLP-1 receptor agonists, like Ozempic (semaglutide for diabetes) or Mounjaro (tirzepatide). Although Wegovy and Ozempic share the same active ingredient, it is specifically designed and dosed for weight loss.

In contrast to Mounjaro (tirzepatide), Wegovy mainly focuses on GLP-1 receptors, while Mounjaro stimulates both GLP-1 and GIP receptors, which may lead to more significant weight loss for some individuals.

Wegovy Weight Loss Injections

Wegovy is part of an expanding category of medications that are changing how obesity is managed, moving away from traditional methods like lifestyle changes or bariatric surgery. Its success in weight loss studies has led to more research into its potential benefits for conditions such as cardiovascular disease, nonalcoholic steatohepatitis (NASH), and beyond.

Wegovy Reviews

Wegovy (semaglutide) marks a significant breakthrough in treating obesity and overweight. Its capacity to facilitate substantial and lasting weight loss makes it a highly effective choice for those dealing with excess weight and associated health issues. However, it should be administered under the guidance of a healthcare professional, with careful monitoring for possible side effects and contraindications.